Which structure surrounds the entire nerve trunk, providing protection and enclosing multiple fascicles?

Which structure surrounds the entire nerve trunk, providing protection and enclosing multiple fascicles?

• A. Perineurium
• B. Endoneurium
• C. Epineurium
• D. Myelin

Answer: (C)

The outermost protective sheath that surrounds the entire nerve trunk and groups multiple fascicles is the epineurium. It’s a layer of dense irregular connective tissue that provides mechanical protection and houses blood vessels and fat, helping cushion and nourish the nerve. Inside the epineurium, each fascicle is wrapped by the perineurium, and each individual axon is enveloped by the endoneurium; myelin is the insulating covering around axons, not a sleeve around the whole nerve.

The outermost protective sheath that surrounds the entire nerve trunk and groups multiple fascicles is the epineurium. It’s a layer of dense irregular connective tissue that provides mechanical protection and houses blood vessels and fat, helping cushion and nourish the nerve. Inside the epineurium, each fascicle is wrapped by the perineurium, and each individual axon is enveloped by the endoneurium; myelin is the insulating covering around axons, not a sleeve around the whole nerve.