Which process forms an isogenous group of chondrocytes?

Which process forms an isogenous group of chondrocytes?

• A. Secretion By Perichondrial Cells
• B. Migration Of Osteoblasts
• C. Proliferation Of A Single Chondrocyte To Form A Cluster
• D. Fusion Of Chondroblasts

Answer: (C)

Isogenous groups come from interstitial growth inside cartilage, where a single chondrocyte divides (mitosis) and its daughter cells stay close together in the surrounding matrix. This cloning within the lacunae creates a cluster of cells that all originate from one parent chondrocyte. So the formation of an isogenous group is driven by the proliferation of a single chondrocyte to form a cluster. Secretion by perichondrial cells contributes to growth at the cartilage surface (appositional growth), not to internal cell clustering. Migration of osteoblasts relates to bone formation, not cartilage. Fusion of chondroblasts is not how these groups form—the cluster arises from division, not fusion.

Isogenous groups come from interstitial growth inside cartilage, where a single chondrocyte divides (mitosis) and its daughter cells stay close together in the surrounding matrix. This cloning within the lacunae creates a cluster of cells that all originate from one parent chondrocyte. So the formation of an isogenous group is driven by the proliferation of a single chondrocyte to form a cluster.

Secretion by perichondrial cells contributes to growth at the cartilage surface (appositional growth), not to internal cell clustering. Migration of osteoblasts relates to bone formation, not cartilage. Fusion of chondroblasts is not how these groups form—the cluster arises from division, not fusion.