Which cell type within the intestinal epithelium secretes mucus?

Which cell type within the intestinal epithelium secretes mucus?

• A. Enteroendocrine cell
• B. Paneth cell
• C. Enterocyte
• D. Goblet cell

Answer: (D)

Goblet cells are the mucus-secreting cells of the intestinal lining. They produce and store mucins in granules and release them into the lumen, forming a protective mucus layer that lubricates the surface and helps trap bacteria. This function distinguishes them from other intestinal cells: enteroendocrine cells release hormones, Paneth cells secrete antimicrobial peptides, and enterocytes focus on nutrient absorption. The mucus barrier provided by goblet cells protects the epithelium and aids immune defense, so they are the ones responsible for mucus secretion.

Goblet cells are the mucus-secreting cells of the intestinal lining. They produce and store mucins in granules and release them into the lumen, forming a protective mucus layer that lubricates the surface and helps trap bacteria. This function distinguishes them from other intestinal cells: enteroendocrine cells release hormones, Paneth cells secrete antimicrobial peptides, and enterocytes focus on nutrient absorption. The mucus barrier provided by goblet cells protects the epithelium and aids immune defense, so they are the ones responsible for mucus secretion.