Pyramidal cells are located in which of the following?

Pyramidal cells are located in which of the following?

• A. Gray matter of cerebrum
• B. White matter of cerebrum
• C. Gray matter of cerebellum
• D. White matter of cerebellum

Answer: (A)

Pyramidal cells are a primary excitatory neuron type that forms the main output of the cerebral cortex. Their cell bodies reside in the gray matter of the cerebrum, especially in cortical layers II/III and V, with a characteristic pyramid-shaped soma and a long apical dendrite plus several basal dendrites. Their axons project to distant cortical areas and subcortical targets, coordinating complex cortical processing. White matter mostly contains myelinated axons and very few neuron cell bodies, while cerebellar gray matter contains different cells (like Purkinje cells). This combination is why the correct location is the gray matter of the cerebrum.

Pyramidal cells are a primary excitatory neuron type that forms the main output of the cerebral cortex. Their cell bodies reside in the gray matter of the cerebrum, especially in cortical layers II/III and V, with a characteristic pyramid-shaped soma and a long apical dendrite plus several basal dendrites. Their axons project to distant cortical areas and subcortical targets, coordinating complex cortical processing. White matter mostly contains myelinated axons and very few neuron cell bodies, while cerebellar gray matter contains different cells (like Purkinje cells). This combination is why the correct location is the gray matter of the cerebrum.