Pyramidal cells are located in the gray matter of which brain region?

Pyramidal cells are located in the gray matter of which brain region?

• A. Gray matter of cerebellum
• B. White matter of cerebrum
• C. Gray matter of cerebrum
• D. White matter of cerebellum

Answer: (C)

Pyramidal cells are a major excitatory neuron type located in the cerebral cortex, which is the gray matter on the outer surface of the cerebrum. Their cell bodies sit in this gray matter, with long apical dendrites extending toward the outer surface and axons that project to other cortical areas and beyond. The cerebrum’s gray matter houses these neuronal cell bodies, while white matter contains mainly myelinated axons, and the cerebellum’s gray matter is known for Purkinje cells, not pyramidal cells. So the correct location is the gray matter of the cerebrum.

Pyramidal cells are a major excitatory neuron type located in the cerebral cortex, which is the gray matter on the outer surface of the cerebrum. Their cell bodies sit in this gray matter, with long apical dendrites extending toward the outer surface and axons that project to other cortical areas and beyond. The cerebrum’s gray matter houses these neuronal cell bodies, while white matter contains mainly myelinated axons, and the cerebellum’s gray matter is known for Purkinje cells, not pyramidal cells. So the correct location is the gray matter of the cerebrum.